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Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial

机译:单次吸入三联疗法与吸入皮质类固醇联合长效β2-激动剂治疗慢性阻塞性肺疾病(TRILOGY):双盲,平行组,随机对照试验

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摘要

Few data are available for the efficacy of "triple therapy" with two long-acting bronchodilators and an inhaled corticosteroid in chronic obstructive pulmonary disease (COPD). We designed this study to assess efficacy of single-inhaler combination of an extra fine formulation of beclometasone dipropionate, formoterol fumarate, and glycopyrronium bromide (BDP/FF/GB) in COPD compared with beclometasone dipropionate and formoterol fumarate (BDP/FF) treatment.
机译:在慢性阻塞性肺疾病(COPD)中,很少有关于使用两种长效支气管扩张药和吸入皮质类固醇的“三联疗法”疗效的数据。我们设计了这项研究,以评估比巴氯米松二丙酸酯和福莫特罗富马酸酯(BDP / FF)治疗的超精细制剂倍氯米松双丙酸酯,福莫特罗富马酸酯和格隆溴铵(BDP / FF / GB)的单吸入器组合在COPD中的疗效。

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